Platelet Rich Plasma Therapy (PRP) Post Op Instructions

Medically Reviewed by Mark Youssef, MD 5 stars from 103 reviews

Activity Restrictions:

• Rest the affected region for at least 48 hours after PRP and minimize excessive movement, stress, and weight loading as much as possible. 
• Your doctor may recommend the temporary use of crutches or other assistive device after lower extremity PRP. A sling may be indicated after shoulder PRP.

Physical Therapy:

• Should be started 3-7 days after PRP. Physical therapy optimizes the effects of PRP and is recommended for most patients. 
• Post-PRP protocol allows therapists to properly rehabilitate the affection region in a safe and efficient manner.

Bracing:

• Your doctor may have prescribed a brace or wrap for you. Wear this after your PRP for up to 5 days. Wearing it while you sleep is not necessary (unless PRISM wraps were prescribed, in which case nights are recommended).
• After 5 days, apply the brace/splint as needed (i.e. with activity, exercise, or walking)

Icing:

• Ice the region 5-7 times a day for 20-minute sessions as need for pain relief and swelling. Heat is fine after the first 72 hours.

Pain Medications:

• For the first 48 hours, swelling and discomfort are typical in the injected area. By day 5, these symptoms will begin to substantially resolve.
• If the pain is not severe, try Tylenol 500mg between 1-2 tablets 3 times a day. For severe pain, take the pain medication prescribed by your doctor every 4- 6 hours (usually Vicoden or Codeine).
• Anti-inflammatories should not be taken after PRP (Advil, Motrin, Aleve, Ibuprofen, Naprosyn)

Supplements:

• Continue to take your supplements as previously determined by your physician.

Follow-up:

• Usually between 4-6 weeks after PRP treatment unless otherwise instructed by your doctor. It typically takes minimum of 6 weeks to see internal healing on ultrasound.